This book constitutes the thoroughly refereed proceedings of the 35th International Conference on Industrial, Engineering and Other Applications of Applied Intelligent Systems, IEA/AIE 2022, held in Kitakyushu, Japan, in July 2022. The 67 full papers and 11 short papers presented were carefully reviewed and selected from 127 submissions. The IEA/AIE 2022 conference focuses on focuses on applications of applied intelligent systems to solve real-life problems in all areas including business and finance, science, engineering, industry, cyberspace, bioinformatics, automation, robotics, medicine and biomedicine, and human-machine interactions.