1. Purpose of this edition (Scope of textbook) 2. Bioprocess Development: An Interdisciplinary Challenge PART 1: FUNDAMENTAL CONCEPTS 3. Microbiology and Biochemistry 4. Material Balances 5. Energy Balances 6. Enzyme and Cell Growth Kinetics PART 2: BIOREACTORS AND TRANSPORT 7. Bioreactors 8. Mixing 9. Bioreactor Mass Transfer 10. Bioreactor Heat Transfer PART 3: PROCESS INTEGRATION AND APPLICATION 11. Unit Operations/Downstream Processing 12. Genetic and Evolutionary Engineering of Organisms for Bioprocessing 13. Process Engineering and Design of Bioprocesses

Includes more than 350 problems that demonstrate how fundamental principles are applied in areas such as biofuels, bioplastics, bioremediation, tissue engineering, site-directed mutagenesis, recombinant protein production, and drug development, as well as for traditional microbial fermentation Provides in-depth treatment of fluid flow, turbulence, mixing, and impeller design, reflecting recent advances in our understanding of mixing processes and their importance in determining the performance of cell cultures Focuses on underlying scientific and engineering principles rather than on specific biotechnology applications, providing a sound basis for teaching bioprocess engineering Presents new or expanded coverage of such topics as enzyme kinetics, downstream processing, disposable reactors, genetic engineering, and the technology of fermentation