The book is the follow-up to its predecessor “Automation, Communication and Cybernetics in Science and Engineering 2009/2010” and includes a representative selection of all scientific publications published between 07/2011 and 06/2012 in various books, journals and conference proceedings by the researchers of the following institute cluster:IMA - Institute of Information Management in Mechanical EngineeringZLW - Center for Learning and Knowledge ManagementIfU - Associated Institute for Management CyberneticsFaculty of Mechanical Engineering, RWTH Aachen UniversityInnovative fields of application, such as cognitive systems, autonomous truck convoys, telemedicine, ontology engineering, knowledge and information management, learning models and technologies, organizational development and management cybernetics are presented.