"A valuable addition to the literature by any measure and surely will prove its merit in years to come. The new knowledge that arises with its help will be impressive and of great benefit to humankind."
From the Foreword by E. J. Corey, Nobel Prize Laureate

An invaluable guide to name reactions and reagents for homologations

Name Reactions for Homologations, Part II of Wiley's Comprehensive Name Reactions series comprises a comprehensive treatise on name reactions for homologations. With contributions from world-recognized authorities in the field, this reference offers an up-to-date, concise compilation of the most commonly used and widely known name reactions and reagents. Part II discusses Rearrangements, Asymmetric C-C Bond Formation, and Miscellaneous Homologation Reactions.

Arranged alphabetically by name reactions, the listing provides:

  • Description of the reaction
  • Historical perspective
  • A mechanism for the reaction
  • Variations and improvements on the reaction
  • Synthetic utilities of the reaction
  • Experimental details
  • References to the current primary literature

Armed with this invaluable resource, both students and professionals will have at their fingertips a comprehensive guide to important mechanisms and phenomena in homologation.

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Part of the "Wiley's Comprehensive Name Reactions" series, this title comprises a comprehensive treatise on name reactions for homologations. It offers a compilation of the most commonly used and widely known name reactions and reagents. It also discusses Rearrangements, Asymmetric C-C Bond Formation, and Miscellaneous Homologation Reactions.
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Foreword.

Preface.

Contributing Authors.

Chapter 1: Rearrangements.

Section 1.1 Concerted rearrangement.

Section 1.2 Cationic rearrangement.

Section 1.3 Anionic rearrangement.

Chapter 2: Asymmetric CC bond formation.

2.1 Evans aldol reaction.

2.2 Hajos-Wiechert reaction.

2.3 Keck stereoselective allylation.

2.4 Roush allylboronation.

Chapter 3: Miscellaneous homologation reactions.

3.1 Bamford-Stevens reaction.

3.2 Mannich reaction.

3.3 Mitsunobu reaction.

3.4 Parham cyclization.

3.5 Passerini reaction.

3.6 Ugi reaction.

Appendixes.

Appendix 1, Table of Contents for Volume 1: Name Reactions in Heterocyclic Chemistry.

Appendix 2, Table of Contents for Volume 2: Name Reactions for Functional Group Transformations.

Appendix 3, Table of Contents for Volume 3: Name Reactions for Homologations-I.

Appendix 4, Table of Contents for Volume 5: Name Reactions for Ring Formations.

Appendix 5, Table of Contents for Volume 6: Name Reactions in Heterocyclic Chemistry-II.

Subject index.

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"Jack Li and his illustrious team of chemists have done it again. It is hard to imagine how one could organize and categorize a topic so broad as "homologation" reactions. These are some of the bread and butter transforms of organic chemistry ? reactions that are fundamentally important to the practice of chemical synthesis. This two book series is masterfully organized and easy to use both as a reference work for the classroom and a springboard for practitioners to rapidly apply these reactions in the laboratory. The extensive coverage of these critical reactions, including a historical perspective, mechanism, synthetic utility, and actual experimental details will ensure that these books will be on the shelf of every serious organic chemist for years to come."

--Phil S. Baran, The Scripps Research Institute

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Produktdetaljer

ISBN
9780470464984
Publisert
2009-03-31
Utgiver
Vendor
John Wiley & Sons Inc
Vekt
1610 gr
Høyde
244 mm
Bredde
199 mm
Dybde
51 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Innbundet
Antall sider
872

Redaktør
Foreword by

Biographical note

Jie Jack Li is a chemist at Bristol-Myers Squibb Company. He received his BS from Nanjing University and his PhD in organic chemistry at Indiana University. Dr. Li completed a postdoctoral fellowship at MIT. He is coauthor of various books, including Name Reactions in Heterocyclic Chemistry, Contemporary Drug Synthesis, Name Reactions for Functional Group Transformations, Name Reactions for Homologations, Parts I and II, Name Reactions on Ring Formations, and The Art of Drug Synthesis, all published by Wiley.