Contents: Analytical Directions: Central issues in neural spatial interaction modelling: the model selection and the parameter estimation problem, Manfred Fischer; Genetic algorithms and transportation analysis: review and perspectives for bus network optimization, Maurizio Bielli and Pasquale Carotenuto; Winners and losers in spatial duopoly markets: the relevance of a value transfer approach, Frans Bal and Peter Nijkamp; Objective and subjective methods of exploring regional economic disparities, Kenneth Button. Methodological Contributions and Applications in Transport Analysis: Neural network and spatial interaction analysis of European commodity flows, Peter Nijkamp, Aura Reggiani and Enrico Sabella; Estimation of gravity models by OLS estimation, Poisson and Neural network specifications, Erik Bergkvist and Lars Westin; Development of high-speed systems in Europe: multicriteria ranking of alternatives, Milan Janic; Rail network management and competition for transport service provision, Anna Bassanini and Alberto Nastasi. Methodological Contributions and Applications in Spatial Dynamics: R&D investments and knowledge stock formation: a cross country study of innovation and growth, Domenico Campisi, Massimo Gastaldi and Nathan Levialdi; European economic convergency and the entrance of new members in the European Union, Gustav Kristensen and Jie Zhang; Intersectoral technology flows in a biregional model, Tullio Gregori and Gustav Schachter; The spatial dispersion of economic activities and development trends in China: 1952-1985, Tschangho John Kim and Gerrit Knaap.