Metalloproteins and Motor Proteins, Volume 141 focuses on recent advances in studying metalloproteins and motor proteins, along with their roles in different pathologies and drug-resistance. Chapters include Transcriptomic Analysis Reveals Zinc-Mediated Virulence and Pathogenicity in Multidrug-Resistant Acinetobacter baumannii, The Mechanistic Insights into Different Aspects of Promiscuity in Metalloenzymes, Role of Metal ion in ion channel Mechanisms, A model of microtubule depolymerization by kinesin-8 motor proteins, Metalloproteins and metalloproteomics in health and disease, Decoding Genetic and Pathophysiological Mechanisms in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis: A Comparative Study of Differentially Expressed Genes and Implicated Pathways in Motor Neuron Disorders, and much more. Additional chapters cover Exploring the effect of disease causing mutations in metal binding sites of human ARSA in Metachromatic Leukodystrophy, Role of transmembrane proteins in regulating metalloproteins and motor proteins in human cancer, Role of transmembrane proteins in metalloproteins and motor proteinsin human neurogenesis, Role of transmembrane proteins in metalloproteins and motor proteins in human aging, Vesicle transport of metalloproteinases, Motor proteins and spermatogenesis, and much more.
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1. Transcriptomic Analysis Reveals Zinc-Mediated Virulence and Pathogenicity in Multidrug-Resistant Acinetobacter baumannii George Priya Doss C, Hatem Zayed, Santhosh ME, Prasanna Kumar Selvam, Mohanraj Gopikrishnan, Karthick Vasudevan, Mangesh R and Charles Emmanuel Jebaraj W 2. The Mechanistic Insights into Different Aspects of Promiscuity in Metalloenzymes Kshatresh Dutta Dubey and Ankita Tripathi 3. Role of Metal ion in ion channel Mechanisms Selvaraj Chandrabose Sr. 4. A model of microtubule depolymerization by kinesin-8 motor proteins Ping Xie 5. Metalloproteins and metalloproteomics in health and disease Iman Hassan Ibrahim 6. Decoding Genetic and Pathophysiological Mechanisms in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis: A Comparative Study of Differentially Expressed Genes and Implicated Pathways in Motor Neuron Disorders George Priya Doss C and Hatem Zayed 7. Exploring the effect of disease causing mutations in metal binding sites of human ARSA in Metachromatic Leukodystrophy George Priya Doss C, Mangesh R, Hatem Zayed, Karthick Vasudevan, Madhana Priya N, Sidharth Kumar N, Udhaya Kumar S and Mohanraj G 8. Role of transmembrane proteins in regulating metalloproteins and motor proteins in human cancer Rolland Reinbold 9. Role of transmembrane proteins in metalloproteins and motor proteinsin human neurogenesis Rolland Reinbold 10. Role of transmembrane proteins in metalloproteins and motor proteins in human aging Rolland Reinbold 11. Vesicle transport of metalloproteinases Yoshifumi Itoh 12. Motor proteins and spermatogenesis C. Yan Cheng 13. Motor proteins regulates Tauopathy in Neurodegeneration/AD Subashchandrabose Chinnathambi 14. The crosstalk between ECM proteins and Tau Subashchandrabose Chinnathambi 15. Microbial Metalloproteins and its role in xenobiotic degradation and ROS scavenging Krishna Kant Sharma 16. Exploring metalloproteins found in the secretion of venomous species: biological role and therapeutic application Cícero Alves Lopes Júnior, Mikael Kélvin de Albuquerque Mendes, Michely da Silva Sousa, Edivan Carvalho Vieira, Tatianny de Araujo Andrade and Jemmyson Romário de Jesus 17. Studying Metalloproteins by Single-molecule Force Spectroscopy Peng Zheng 18. Coordination, cooperation, competition, crowding and congestion of molecular motors: Theoretical models and computer simulations Ambarish Kunwar 19. Epigenetic dysregulation in cancers by Isocitrate dehydrogenase 2 (IDH2) Anuraj Nayarisseri Sr.
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A great amalgamation of methods for studying structure and function of metalloproteins and motor proteins and their implication in drug design and drug resistance
Integrates experimental and computational methods for studying structure and function of metalloproteins and motor proteins and their implication in drug design Presents timely chapters written by well-renowned authorities in their field Contains a high number of high quality illustrations, figures, and tables and targets a very wide audience of specialists, researchers, and students
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Produktdetaljer

ISBN
9780443193446
Publisert
2024-07-04
Utgiver
Vendor
Academic Press Inc
Vekt
1220 gr
Høyde
229 mm
Bredde
152 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Innbundet
Antall sider
676

Series edited by

Biographical note

Rossen Donev received his PhD degree in 1999 from the Institute of Molecular Biology, Bulgarian Academy of Sciences. He did postdoctoral training at Imperial Cancer Research Fund, UK (renamed after the merger with Cancer Research Campaign to Cancer Research UK, London Research Institute) and Cardiff University. In 2007 he was awarded a New Investigator Grant Award from the Medical Research Council (UK) to establish himself as an independent Principle Investigator. In 2010 Dr. Donev was appointed Senior Lecturer at Swansea University. In 2016 Dr. Donev joined MicroPharm Ltd (UK) where currently he is Head of Research. He has published more than 60 research papers, chaired scientific meetings and given invited plenary talks. Rossen Donev has consulted on projects related to development of treatments for neurodevelopmental disorders and cancer therapies. He serves as Editor-in-Chief of the Advances in Protein Chemistry and Structural Biology and on editorial board of several other journals. His research interests include signaling pathways involved in neuropsychiatric disorders and tumor escape from the immune system, and development of therapeutic strategies for their treatment. More recently he has focused on development of immunotherapeutics for non-systemic applications.