_Sinusoidal Cells in Liver Diseases: Role in their Pathophysiology,
Diagnosis, and Treatment_ provides a state-of-the-art review on recent
advances surrounding the role of liver sinusoidal cells (LSECs, HSCs,
macrophages, and other non-parenchymal cells) in acute and chronic
liver diseases. Coverage emphasizes disease pathophysiology, novel
mechanisms, unmet clinical questions, development of biomarkers and
treatment opportunities. By focusing on the role of sinusoidal cells
in human liver diseases, this reference provides a comprehensive
overview of the role of sinusoidal cells in acute and chronic liver
diseases, in its pathophysiology and mechanisms, and in the
development of novel biomarkers and new therapeutics.
Cells of the liver vasculature play an essential role in the
pathophysiology of acute and chronic liver diseases and are considered
key therapeutic targets to treat most of human hepatopathies. Coverage
in this reference includes the phenotypic changes occurring in liver
vascular cells and how cells contribute to the development of
microcirculatory dysfunction, fibrosis, inflammation, and liver
failure.
* Provides a comprehensive update on the role of sinusoidal cells in
acute and chronic liver diseases
* Covers our current understanding of the role of sinusoidal cells as
therapeutic targets to improve liver diseases
* Presents the latest research in the development of novel biomarkers
of liver diseases that derive from sinusoidal cells
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Role in their Pathophysiology, Diagnosis, and Treatment
Produktdetaljer
ISBN
9780323952637
Publisert
2024
Utgave
1. utgave
Utgiver
Vendor
Academic Press
Språk
Product language
Engelsk
Format
Product format
Digital bok
Forfatter