Reverse Vaccinology: Concept, Methods, and Advancement presents the development strategy of new vaccines through genome sequencing bioinformatics analysis. This book promises to revolutionize vaccine development, especially for pathogens to which the classical applications of Pasteur’s principles have failed, and it is explained in detail in this book.
This book is split into three sections: the first, Concept, brings the basis of reverse vaccinology, vaccine antigen discovery, and subunit vaccine; the second, Tools and Methods, describes immunoinformatic, proteomics for epitope-vaccine design, databases, network analysis, machine learning, and NGS-driven antigen screening technology; and the last one, Disease Case Study, discusses real-world examples in the development of new vaccines for diverse diseases.
It is a valuable resource for bioinformaticians, researchers, students, and members of the biomedical and medical fields who want to learn more about a new and agile process for the development of new vaccines.
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1. Personalized vaccinology
2. Novel vaccine adjuvants formulations and mechanisms of action
3. Technologies to measure vaccine immune response against infectious diseases
4. Vaccines for cancer
5. Vaccines against autoimmune diseases
6. Vaccines for allergy
7. Virus vaccine production using cell-based technology
8. Dendritic cell-based cancer vaccine production
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Discusses reverse vaccinology as an agile method for vaccine development
Explains the fundamentals of reverse vaccinology and how it can save time in the development of new vaccines
Focuses on the efforts to develop a vaccine candidate against various pathogens using computational approaches
Presents databases and web servers for conducting reverse vaccinology
Describes the screening process of potential vaccine candidate through machine learning
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Produktdetaljer
ISBN
9780443133954
Publisert
2024-07-11
Utgiver
Vendor
Academic Press Inc
Vekt
620 gr
Høyde
229 mm
Bredde
152 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
382