1. Lighting up the central dogma for predictive developmental biology Hernan G. Garcia, Augusto Berrocal, Yang Joon Kim, Gabriella Martini and Jiaxi Zhao 2. Optogenetic approaches to investigate spatiotemporal signaling during development Katherine W. Rogers and Patrick Müller 3. A matter of time: Formation and interpretation of the Bicoid morphogen gradient Anqi Huang and Timothy E. Saunders 4. Constraints and limitations on the transcriptional response downstream of the Bicoid morphogen gradient Huy Tran, Aleksandra M. Walczak and Nathalie Dostatni 5. Formation, interpretation, and regulation of the Drosophila Dorsal/NF-ΚB gradient Allison E. Schloop, Prasad U. Bandodkar and Gregory T. Reeves 6. The design and logic of terminal patterning in Drosophila Celia M. Smits and Stanislav Y. Shvartsman 7. Dynamic positional information: Patterning mechanism versus precision in gradient-driven systems Johannes Jaeger and Berta Verd 8. Intracellular morphogens: Specifying patterns at the subcellular scale Lars Hubatsch and Nathan W. Goehring 9. Insights into mammalian morphogen dynamics from embryonic stem cell systems Elena Camacho-Aguilar and Aryeh Warmflash 10. Control of size, fate and time by the Hh morphogen in the eyes of flies David G. Miguez, Diana Garcia-Morales and Fernando Casares 11. Genetic mechanisms controlling anterior expansion of the central nervous system Behzad Yaghmaeian Salmani and Stefan Thor 12. Temporal dynamics in the formation and interpretation of Nodal and BMP morphogen gradients Andrew D. Economou and Caroline S. Hill 13. Signaling regulation during gastrulation: Insights from mouse embryos and in vitro systems Sophie M. Morgani and Anna-Katerina Hadjantonakis 14. Just passing through: The auxin gradient of the root meristem Bruno Guillotin and Kenneth D. Birnbaum 15. Small RNAs as plant morphogens Simon Klesen, Kristine Hill and Marja C.P. Timmermans

Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology series Includes the latest information on gradients and tissue patterning