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Functional Nucleic Acids for Analytical Applications

Li Yingfu Lu Yi
Innbundet / 2008 / Engelsk

Produktdetaljer

ISBN
9780387737102
Publisert
2008-12-12
Utgiver
Vendor
Springer-Verlag New York Inc.
Høyde
235 mm
Bredde
155 mm
Aldersnivå
Research, UU, UP, 05
Språk
Product language
Engelsk
Format
Product format
Innbundet

Redaktør
Li Yingfu
Lu Yi

Functional Nucleic Acids for Analytical Applications

Li Yingfu Lu Yi
Innbundet / 2008 / Engelsk
Li Yingfu Lu Yi
Innbundet / 2008 / Engelsk
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<p>From the reviews:</p><p></p><p>"This book consists of 15 chapters contributed by experts in the field of functional nucleic acids, mostly in the area of specific analytical applications of nucleic acids … . this book affords a comprehensive collection of clearly presented, up-to-date reviews that broadly cover the numerous applications of functional nucleic acids. … The chapters are of high quality … that will be useful to newcomers entering the field of functional nucleic acids and to those interested in exploring other applications complementary to their own niches." (Jennifer S. Brodbelt, Journal of the American Chemical Society, Vol. 131 (32), 2009)</p><p>“The book is well structured and combines 15 insightful reviews written by many leading experts. … Functional Nucleic Acids for Analytical Applications is a comprehensive and well written book. With its excellent review of recent progress and critical outlook of future directions it will be very valuable for researchers wishing to explore the unique properties of FNAs for different applications in analytical and bioanalytical chemistry.”­­­ (Xiaohong Fang, Analytical and Bioanalytical Chemistry, Vol. 398, June, 2010)</p>

Nature has long used nucleic acid aptamers and enzymes for regulatory activities, such as the recently discovered “riboswitches” involved in gene expression. The existence of a large array of natural and artificial functional nucleic acids has generated tremendous enthusiasm and new opportunities for molecular scientists from diverse disciplines to devise new concepts and real applications that take advantage of those nucleic acids for sensing and other analytical applications. This book provides a timely and comprehensive overview of recent advances in the field, from leading experts in biology, chemistry, and engineering. A variety of topics are covered, from fundamentals of functional nucleic acids, to their applications as sensors, to nanotechnologies; as well as integration of functional nucleic acids into practical analytical systems.
Les mer
The existence of a large array of natural and artificial functional nucleic acids has generated tremendous enthusiasm and new opportunities for molecular scientists from diverse disciplines to devise new concepts and real applications that take advantage of those nucleic acids for sensing and other analytical applications.
Les mer
Overview of Functional Nucleic Acids and Their Analytical Applications.- Introductory Remarks.- Natural Functional Nucleic Acids: Ribozymes and Riboswitches.- Artificial Functional Nucleic Acids: Aptamers, Ribozymes, and Deoxyribozymes Identified by In Vitro Selection.- Functional Nucleic Acid Sensors Based on Different Transduction Principles.- Fluorescent Aptamer Sensors.- Fluorescent Ribozyme and Deoxyribozyme Sensors.- Colorimetric and Fluorescent Biosensors Based on Directed Assembly of Nanomaterials with Functional DNA.- Electrochemical Approaches to Aptamer-Based Sensing.- Amplified DNA Biosensors.- Other Emerging Analytical Applications.- Aptamers in Affinity Separations:Capillary Electrophoresis.- Aptamers in Affinity Separations: Stationary Separation.- Aptamer Microarrays.- The Use of Functional Nucleic Acids in Solid-Phase Fluorimetric Assays.- Functional Nucleic Acid Sensors as Screening Tools.- Nucleic Acids for Computation.- DNAzymes in DNA Nanomachines and DNA Analysis.
Les mer
Both DNA and RNA can serve purposes beyond simple genetic storage and transfer – for example, they can also be employed as enzymes (for catalysis) and receptors (for ligand binding). Increasingly, researchers are making interesting use of these molecules, now collectively called functional nucleic acids. This book, containing chapters written by leading experts in relevant fields, provides timely accounts of diverse analytical applications that take advantage of the functional nucleic acids. The book is written for academic, clinical and industrial scientists and graduate students who may consider exploring functional nucleic acids in their research or practice.
Les mer
First in the rapidly emerging field on analytical applications for nucleic acids With interdisciplinary approach, a valuable tool for researchers in chemistry, biology, and engineering One of the first books in the series Integrated Microanalytical Systems, recently renamed Integrated Analytical Systems, edited by R. Potyrailo
Les mer

Relaterte produkter

<p>From the reviews:</p><p></p><p>"This book consists of 15 chapters contributed by experts in the field of functional nucleic acids, mostly in the area of specific analytical applications of nucleic acids … . this book affords a comprehensive collection of clearly presented, up-to-date reviews that broadly cover the numerous applications of functional nucleic acids. … The chapters are of high quality … that will be useful to newcomers entering the field of functional nucleic acids and to those interested in exploring other applications complementary to their own niches." (Jennifer S. Brodbelt, Journal of the American Chemical Society, Vol. 131 (32), 2009)</p><p>“The book is well structured and combines 15 insightful reviews written by many leading experts. … Functional Nucleic Acids for Analytical Applications is a comprehensive and well written book. With its excellent review of recent progress and critical outlook of future directions it will be very valuable for researchers wishing to explore the unique properties of FNAs for different applications in analytical and bioanalytical chemistry.”­­­ (Xiaohong Fang, Analytical and Bioanalytical Chemistry, Vol. 398, June, 2010)</p>

Nature has long used nucleic acid aptamers and enzymes for regulatory activities, such as the recently discovered “riboswitches” involved in gene expression. The existence of a large array of natural and artificial functional nucleic acids has generated tremendous enthusiasm and new opportunities for molecular scientists from diverse disciplines to devise new concepts and real applications that take advantage of those nucleic acids for sensing and other analytical applications. This book provides a timely and comprehensive overview of recent advances in the field, from leading experts in biology, chemistry, and engineering. A variety of topics are covered, from fundamentals of functional nucleic acids, to their applications as sensors, to nanotechnologies; as well as integration of functional nucleic acids into practical analytical systems.
Les mer
The existence of a large array of natural and artificial functional nucleic acids has generated tremendous enthusiasm and new opportunities for molecular scientists from diverse disciplines to devise new concepts and real applications that take advantage of those nucleic acids for sensing and other analytical applications.
Les mer
Overview of Functional Nucleic Acids and Their Analytical Applications.- Introductory Remarks.- Natural Functional Nucleic Acids: Ribozymes and Riboswitches.- Artificial Functional Nucleic Acids: Aptamers, Ribozymes, and Deoxyribozymes Identified by In Vitro Selection.- Functional Nucleic Acid Sensors Based on Different Transduction Principles.- Fluorescent Aptamer Sensors.- Fluorescent Ribozyme and Deoxyribozyme Sensors.- Colorimetric and Fluorescent Biosensors Based on Directed Assembly of Nanomaterials with Functional DNA.- Electrochemical Approaches to Aptamer-Based Sensing.- Amplified DNA Biosensors.- Other Emerging Analytical Applications.- Aptamers in Affinity Separations:Capillary Electrophoresis.- Aptamers in Affinity Separations: Stationary Separation.- Aptamer Microarrays.- The Use of Functional Nucleic Acids in Solid-Phase Fluorimetric Assays.- Functional Nucleic Acid Sensors as Screening Tools.- Nucleic Acids for Computation.- DNAzymes in DNA Nanomachines and DNA Analysis.
Les mer
Both DNA and RNA can serve purposes beyond simple genetic storage and transfer – for example, they can also be employed as enzymes (for catalysis) and receptors (for ligand binding). Increasingly, researchers are making interesting use of these molecules, now collectively called functional nucleic acids. This book, containing chapters written by leading experts in relevant fields, provides timely accounts of diverse analytical applications that take advantage of the functional nucleic acids. The book is written for academic, clinical and industrial scientists and graduate students who may consider exploring functional nucleic acids in their research or practice.
Les mer
First in the rapidly emerging field on analytical applications for nucleic acids With interdisciplinary approach, a valuable tool for researchers in chemistry, biology, and engineering One of the first books in the series Integrated Microanalytical Systems, recently renamed Integrated Analytical Systems, edited by R. Potyrailo
Les mer

Produktdetaljer

ISBN
9780387737102
Publisert
2008-12-12
Utgiver
Vendor
Springer-Verlag New York Inc.
Høyde
235 mm
Bredde
155 mm
Aldersnivå
Research, UU, UP, 05
Språk
Product language
Engelsk
Format
Product format
Innbundet

Redaktør
Li Yingfu
Lu Yi

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