This book constitutes the refereed proceedings of the Third MICCAI Workshop on Domain Adaptation and Representation Transfer, DART 2021, and the First MICCAI Workshop on Affordable Healthcare and AI for Resource Diverse Global Health, FAIR 2021, held in conjunction with MICCAI 2021, in September/October 2021. The workshops were planned to take place in Strasbourg, France, but were held virtually due to the COVID-19 pandemic.DART 2021 accepted 13 papers from the 21 submissions received. The workshop aims at creating a discussion forum to compare, evaluate, and discuss methodological advancements and ideas that can improve the applicability of machine learning (ML)/deep learning (DL) approaches to clinical setting by making them robust and consistent across different domains. For FAIR 2021, 10 papers from 17 submissions were accepted for publication. They focus on Image-to-Image Translation particularly for low-dose or low-resolution settings; Model Compactness and Compression; Domain Adaptation and Transfer Learning; Active, Continual and Meta-Learning.

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Domain Adaptation and Representation Transfer.- A Systematic Benchmarking Analysis of Transfer Learning for Medical Image Analysis.- Self-supervised Multi-scale Consistency for Weakly Supervised Segmentation Learning.- FDA: Feature Decomposition and Aggregation for Robust Airway Segmentation.- Adversarial Continual Learning for Multi-Domain Hippocampal Segmentation.- Self-Supervised Multimodal Generalized Zero Shot Learning For Gleason Grading.- Self-Supervised Learning of Inter-Label Geometric Relationships For Gleason Grade Segmentation.- Stop Throwing Away Discriminators! Re-using Adversaries for Test-Time Training.- Transductive image segmentation: Self-training and effect of uncertainty estimation.- Unsupervised Domain Adaptation with Semantic Consistency across Heterogeneous Modalities for MRI Prostate Lesion Segmentation.- Cohort Bias Adaptation in Federated Datasets for Lesion Segmentation.- Exploring Deep Registration Latent Spaces.- Learning from Partially Overlapping Labels: Image Segmentation under Annotation Shift.- Unsupervised Domain Adaption via Similarity-based Prototypes for Cross-Modality Segmentation.- A ordable AI and Healthcare.- Classification and Generation of Microscopy Images with Plasmodium Falciparum via Arti cial Neural Networks using Low Cost Settings.- Contrast and Resolution Improvement of POCUS Using Self-Consistent CycleGAN.- Low-Dose Dynamic CT Perfusion Denoising without Training Data.- Recurrent Brain Graph Mapper for Predicting Time-Dependent Brain Graph Evaluation Trajectory.- COVID-Net US: A Tailored, Highly Efficient, Self-Attention Deep Convolutional Neural Network Design for Detection of COVID-19Patient Cases from Point-of-care Ultrasound Imaging.- Inter-Domain Alignment for Predicting High-Resolution Brain Networks Using Teacher-Student Learning.- Sickle Cell Disease Severity Prediction from Percoll Gradient Images using Graph Convolutional Networks.- Continual Domain Incremental Learning for Chest X-ray Classificationin Low-Resource Clinical Settings.- Deep learning based Automatic detection of adequately positioned mammograms.- Can non-specialists provide high quality Gold standard labels in challenging modalities.

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