This book presents original research on the theory of positive operators, alongside fixed-point theorems and their diverse applications. It introduces various positive operators and explores their approximation properties, including Korovkin-type theorems, Voronovskaja-type results, convergence rate, and other related findings. Additionally, the book addresses the existence of solutions for various differential and integral equations in different Banach spaces by using Darbo-type fixed-point theorems. This book also presents an interplay between positive operators and fixed-point theory. Each chapter is self-contained, addressing a current problem and outlining solutions and potential applications. The chapters provide sufficient background to ensure that new definitions and results can be understood independently.