Molecularly imprinted polymers (MIPs) are an important functional material because of their potential implications in diverse research fields. The materials have been developed for a range of uses including separation, environmental, biomedical and sensor applications.

Preface xiii Part 1 Strategies of Affinity Materials 1 Recent Molecularly Imprinted Polymer-based Methods for Sample Preparation 3 Antonio Martín-Esteban 1.1 Introduction 3 1.2 Molecularly Imprinted Solid-phase Extraction 6 1.3 Molecularly Imprinted Solid-phase Microextraction 14 1.4 Molecularly Imprinted Stir Bar Sorptive Extraction 17 1.5 Other Formats 18 1.6 Conclusions 20 References 21 2 A Genuine Combination of Solvent-free Sample Preparation Technique and Molecularly Imprinted Nanomaterials 29 Santanu Patra, Ekta Roy, Rashmi Madhuri and Prashant K. Sharma 2.1 Introduction 30 2.2 Molecularly Imprinted Polymer Modified Fiber for Solid-phase Microextraction 40 2.3 In-tube Solid-phase Microextraction Technique 55 2.4 Monolithic Fiber 58 2.5 Micro-solid-phase Extraction 70 2.6 Stir-bar Sorptive Extraction 73 2.7 Conclusion and Future Scope 76 Acknowledgments 76 Abbreviations 77 References 78 3 Fluorescent Molecularly Imprinted Polymers 89 Kornelia Gawlitza, Wei Wan, Sabine Wagner and Knut Rurack 3.1 Introduction 89 3.2 Classes of Emitters to Endow MIPs with Fluorescence 91 3.3 Fluorescent Molecularly Imprinted Silica 108 3.4 Post-imprinting of MIPs 111 3.5 fMIPs as Labels 113 3.6 Formats for fMIPs 115 3.7 Conclusion 119 References 120 4 Molecularly Imprinted Polymer-based Micro- and Nanotraps for Solid-phase Extraction 129 Rıdvan Say, Rüstem Keçili and Arzu Ersöz 4.1 Introduction 130 4.2 MIPs as SPE Materials 130 4.3 Conclusions 149 References 153 5 Imprinted Carbonaceous Nanomaterials: A Tiny Looking Big Thing in the Field of Selective and Secific Analysis 165 Ekta Roy, Santanu Patra, Rashmi Madhuri and Prashant K. Sharma 5.1 Introduction 166 5.2 Graphene-modified Imprinted Polymer 179 5.3 Carbon Nanotubes-modified Imprinted Polymer 190 5.4 Combination of graphene, CNTs, and MIPs 197 5.5 Graphene Quantum Dots and/or Carbon Dots 198 5.6 Fullerene 201 5.7 Activated carbon 202 5.8 Conclusions 203 Acknowledgments 204 List of abbreviations 204 References 205 6 Molecularly Imprinted Materials for Fiber-optic Sensor Platforms 217 Yavuz Orhan Yaman, Necdet Başaran, Kübra Karayagiz, Zafer Vatansever, Cengiz Yegin, Önder Haluk Tekbaş and Müfrettin Murat Sari 6.1 Introduction 218 6.2 Material Aspect: Morphology and Physical Forms of MIPs in FO Sensors 223 6.3 Molecularly Imprinting Technology for Fiber-optic Sensors 231 6.4 State-of-the-art Fiber-optic Sensors Applications Using Molecularly Imprinted Materials 268 6.5 Conclusion 273 References 274 Part 2 Rational Design of MIP for Advanced Applications 7 Molecularly Imprinted Polymer-based Sensors for Biomedical and Environmental Applications 285 Anca Florea, Oana Hosu, Bianca Ciui and Cecilia Cristea 7.1 Introduction 285 7.2 Molecularly Imprinted Polymers for Analytes of Biomedical Interest 296 7.3 Molecularly Imprinted Polymers for Analytes of Environmental Interest 306 7.4 Conclusion 314 Acknowledgments 316 References 316 8 Molecularly Imprinted Polymers: The Affinity Adsorbents for Environmental Biotechnology 327 Bo Mattiasson and Gizem Ertürk 8.1 Introduction 327 8.2 Molecularly Imprinted Polymers 329 8.3 Monomers 329 8.4 Cross-linking Agents 331 8.5 Mode of Polymerization 332 8.6 Cryogels 334 8.7 Process Technology 336 8.8 Applications 338 References 345 9 Molecular Imprinting Technology for Sensing and Separation in Food Safety 353 Baran Önal Ulusoy, Mehmet Odabaşi and Neşe Hayat Aksoy 9.1 Food Safety 354 9.2 Food Analysis 355 9.3 Current Separation Methods Used for Food Safety Purposes 356 9.4 What Is MIP? 357 9.5 MIP Applications Used for Food Safety Purposes 359 References 377 10 Advanced Imprinted Materials for Virus Monitoring 389 Zeynep Altintas 10.1 Introduction 390 10.2 Virus Imprinting 393 10.3 Artificial MIP Receptors for Viruses 398 10.4 Virus Monitoring and Detection Using Biomimetic Sensors 399 10.5 Virus Imprinting for Separation Technologies 401 10.6 Conclusions 405 References 406 11 Design and Evaluation of Molecularly Imprinted Polymers as Drug Delivery Systems 413 André Luís Morais Ruela and Gislaine Ribeiro Pereira 11.1 Introduction 414 11.2 Synthesis and Characterization of MIPs Intended for Drug Release Using Non-covalent Approaches 418 11.3 Design and Evaluation of Drug Delivery Systems Based on MIPs 436 11.4 Conclusions 445 References 446 12 Molecularly Imprinted Materials for Controlled Release Systems 455 Yagmur Yegin, Gökhan Yilmaz, Ömer Karakoç, Cengiz Yegin, Servet Çete, Mustafa Akbulut and Müfrettin Murat Sari 12.1 Introduction 456 12.2 Selectivity, Release Mechanism and Functionality of MIPs-based CR Systems 459 12.3 Molecularly Imprinted Polymers Production for Controlled Release 482 12.4 Controlled Release Applications Using Molecularly Imprinted Materials-based Controlled Release 491 12.5 Conclusion 506 References 507 13 Molecular Imprinting: The Creation of Biorecognition Imprints on the Biosensor Surfaces 523 Gizem Ertürk and Bo Mattiasson 13.1 Introduction 523 13.2 Molecular Imprinting 524 13.3 Microcontact Imprinting 525 13.4 Capacitive Biosensors 529 13.5 Surface Plasmon Resonance Biosensors 541 13.6 Concluding Remarks 549 References 550 14 Molecular Imprinted Polymers for Sensing of Volatile Organic Compounds in Human Body Odor 561 Sunil Kr. Jha 14.1 Introduction 562 14.2 MIP-QCM Sensor Array Preparation 573 14.3 Chemical Vapor Sensing 576 14.4 Analysis Outcomes 603 14.5 Conclusion 624 Acknowledgments 624 References 624 15 Development of Molecularly Imprinted Polymer-based Microcantilever Sensor System 637 Meltem Okan and Memed Duman 15.1 Introduction to Mass Sensors 637 15.2 Principles of Mass Sensors 640 15.4 Molecularly Imprinted Polymer Technology 655 15.5 Molecularly Imprinted Polymer-based QCM Sensors 658 15.6 Ongoing Studies on Molecularly Imprinted Polymers-based Microcantilevers 661 Acknowledgments 669 References 669