This book constitutes the refereed joint proceedings of the 11th International Workshop on Multimodal Learning for Clinical Decision Support, ML-CDS 2021, held in conjunction with the 24th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2021, in Strasbourg, France, in October 2021.

From Picoscale Pathology to Decascale Disease: Image Registration with a Scattering Transform and Varifolds for Manipulating Multiscale Data.- Multi-Scale Hybrid Transformer Networks: Application to Prostate Disease Classification.- Predicting Treatment Response in Prostate Cancer Patients Based on Multimodal PET/CT for Clinical Decision Support.- A Federated Multigraph Integration Approach for Connectional Brain Template Learning.- SAMA: Spatially-Aware Multimodal Network with Attention for Early Lung Cancer Diagnosis.- Fully Automatic Head and Neck Cancer Prognosis Prediction in PET/CT.- Feature Selection for Privileged Modalities in Disease Classification.- Merging and Annotating Teeth and Roots from Automated Segmentation of Multimodal Images.- Structure and Feature based Graph U-Net for Early Alzheimer's Disease Prediction.- A Method for Predicting Alzheimer's Disease based on the Fusion of Single Nucleotide Polymorphisms and Magnetic Resonance Feature Extraction.