This book contains the extended and revised versions of selected papers from the 4th International Symposium on Business Modeling and Software Design, BMSD 2014, held in Luxembourg, Luxembourg, in June 2014. The symposium was organized and sponsored by the Interdisciplinary Institute for Collaboration and Research on Enterprise Systems and Technology (IICREST), in collaboration with the Public Research Centre Henri Tudor (TUDOR). Cooperating organizations were the Dutch Research School for Information and Knowledge Systems (SIKS), Aristotle University of Thessaloniki (AUTH), the UTwente Center for Telematics and Information Technology (CTIT), and AMAKOTA Ltd.The 37 papers presented at BMSD 2014 were selected from 52 submissions. The seven papers published in this book were carefully reviewed, selected, revised, and extended from the presented papers. The selection considers a large number of BMSD-relevant research topics: from modeling and simulation-related subjects, such as declarative business rules, business (process) modeling, business process simulation, and information systems modeling, through architectures-related areas, such as impact analysis with regard to enterprise architectures and architectural principles for service cloud applications, to topics touching upon quality-of-service-aware service systems.