In recent years, nucleic acid technologies have grown into powerful analytical and therapeutic tools. This book details in-depth the potential of these tools in the broad field of the central nervous system, particularly regarding brain tumors.

Molecular Biology of Malignant Gliomas.- Molecular Neurooncology and Neoangiogenesis of Malignant Gliomas.- Molecular Therapies for Malignant Gliomas.- Novel Strategies for the Treatment of Brain Cancer.- Gene Therapy for Malignant Glioma.- Immunotherapeutic Approach for Glioma by Alphaviruses as Positive Strand RNA Viruses.- Diagnosis of Brain Tumors Through Global Specific DNA Methylation Analysis.- Molecular Markers of Gliomas.- Microarray and Proteomic Analysis of Gliomas: Target Strategies.- Nanosystems for the Delivery of RNAi.- Interference RNA Intervention in Brain Tumors.- Blood-Brain Barrier Transport for RNAi.- Therapeutic Potential of Small Interfering RNA for Brain Diseases.- RNA Interference-Based Therapies Against Brain Tumors: Potential Clinical Strategies.- MicroRNA: Biogenesis, Regulation, and Role in Primary Brain Tumors.- Treatment of High-Grade Gliomas in Adults.- Treatment of Malignant Gliomas with Antisense Oligonucleotides.- Suppression of EGFR Expression by Antisense RNA and RNAi.- Brain Tumor Therapy with Antisense Oligonucleotides.- Noncoding RNAs in the Development, Function and Pathologies of the Central Nervous System.- The Non-Coding Oncofetal H19 Gene in Brain Tumors.

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