This volume starts with an elementary introduction covering stem cell methodologies used to produce specific types of neurons, possibilities for their therapeutic use, and warnings of technical problems. In addition the authors report successes in achieving the derivation of a specific type of neuron. The dopamine neuron offers an important example and is discussed in more detail. Additional chapters cover problems obviously approachable with cells derived from stem cells, including their need in surgeries for pituitary cancers. The last chapter provides an overview of this particular field of research and presents a vision for its future directions.
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This volume starts with an elementary introduction covering stem cell methodologies used to produce specific types of neurons, possibilities for their therapeutic use, and warnings of technical problems.
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A brief overview of techniques for modulating neuroendocrine and other neural systems.- Basics of stem cell biology as applied to the brain.- Human pluripotent-derived lineages for repairing hypopituitarism.- Recapitulating hypothalamus and pituitary development using ES/iPS cells.- Regulation of body weight and metabolism by tanycyte-derived neurogenesis in young adult mice.- Genetic dissection of the neuroendocrine and behavioral responses to stressful challenges.- Pituitary stem cells: quest for hidden functions.- Pituitary stem cells during normal physiology and disease.- Epigenetic mechanisms of pituitary cell fate specification.- Advances in stem cells biology: new approaches to understand depression.- Perspective on stem cells in developmental biology, with special reference to neuroendocrine systems.
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This volume starts with an elementary introduction covering stem cell methodologies used to produce specific types of neurons, possibilities for their therapeutic use, and warnings of technical problems. In addition the authors report successes in achieving the derivation of a specific type of neuron. The dopamine neuron offers an important example and is discussed in more detail. Additional chapters cover problems obviously approachable with cells derived from stem cells, including their need in surgeries for pituitary cancers. The last chapter provides an overview of this particular field of research and presents a vision for its future directions.
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Covers the application of stem cell biology to neuroscience Casts new light on the use of stem cells in surgeries of pituitary cancers Discusses technical challenges and solutions Includes supplementary material: sn.pub/extras
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Open Access This book is licensed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made. The images or other third party material in this book are included in the book's Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the book's Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
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Produktdetaljer
ISBN
9783319823942
Publisert
2018-04-22
Utgiver
Vendor
Springer International Publishing AG
Høyde
235 mm
Bredde
155 mm
Aldersnivå
Research, P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet