Health information about patients is critical; currently, health records are saved in databases controlled by individual users, organizations, or large groups of organizations. As there are many malicious users, this information is not shared with other organizations due to security issues and the chance of the data being modified or tampered with. Blockchain can be used to securely exchange healthcare data, which can be accessed by organizations sharing the same network, allowing doctors/practitioners to provide better care for patients. The key properties of decentralization, such as immutability and transparency, improve healthcare interoperability. This book brings forth the prospects and research trends of Blockchain in healthcare, so that Researchers, Database professionals, Academia, and Healthcare professionals across the world can know/use the concept of Blockchain in healthcare. The book provides the fundamental and technical details of Blockchain, the applications of Blockchain in healthcare, hands-on chapters for graduate/postgraduate/doctoral students/healthcare professionals to secure healthcare data of patients, and research challenges and future work directions for researchers in healthcare.