The third edition of the definitive international reference book on all aspects of the medical care of older persons will provide every physician involved in the care of older patients with a comprehensive resource on all the clinical problems they are likely to encounter, as well as on related psychological, philosophical, and social issues.

Section 1: Ageing population and policyEdited by Jean-Pierre Michel: 1: David E. Bloom, Elizabeth Mitgang, and Benjamin Osher: Demography of Global Ageing 2: Emily M Grundy and Michael Murphy: Population ageing in Europe 3: Eileen M. Crimmins, Hiram Beltran-Sanchez, Lauren Brown and Yongjie Yon: Ageing in North America: Canada and the United States 4: Carlos M. Paixao Junior, Roberto A. Lourenço and Morales-Martinez: Population ageing in south and central America 5: Bilkish Cassim and Isabella Aboderin: Population ageing in sub-Saharan Africa 6: Du Peng and Cao Ting: Population ageing in Asia 7: Abla Mehio Sibai and Anthony Rizk: Population Ageing in Arab countries 8: Leon Flicker and Ngaire Kerse: Population Ageing in Oceania 9: Jean-Marie Robine and Carol Jagger: Health expectancies 10: Ruth Bell and Michael Marmot: Life course approach to understanding inequalities in health in later life 11: John R Beard, Anne Margriet Pot, and Geeske Peeters: Implications of population ageing for societies and governments 12: Andrew Mason and Ronald Lee: Economic implications of Population Ageing 13: Alexandre Sidorenko and Alan Walker: Policy options for responding to population ageing Section 2: Key Concepts in care of older adultsEdited by Finbarr C. Martin: 14: H E Syddall and A A Sayer: A lifecourse approach for understanding later life sustainability 15: Barbara Gryglewska, Karolina Piotrowicz and Tomasz Grodzicki: Ageing, multimorbidity and daily functioning 16: Alberto Pilotto and Francesco Panza: Comprehensive Geriatric Assessment: Evidence 17: George Heckman and Pálmi V. Jónsson: Comprehensive Geriatric Assessment: The Specific Assessment Technology of InterRAI 18: Angela Coulter: Engaging older patients in their treatment and care 19: Kaisu Pitkala, John Gladman and Martin Connolly: Models of health care for older people 20: José M Ribera-Casado: History Taking And Physical Examination 21: Rebecca Allwood, Rowan H Harwood: Communication 22: Ellen Flaherty and Terry Fulmer: Interprofessional Team Building and Case Management 23: Lisa Warth, Alana Margaret Officer, John Roland Beard and Norah Keating: Age-friendly environments and their role in supporting Healthy Ageing 24: David G Le Couteur, Andrew J McLachlan and Sarah N Hilmer: Principles Of Medication Management 25: Denis O Mahony: Optimizing Pharmacotherapy for Older Patients 26: Antonio Cherubini and Graziano Onder: Limitations in the evidence for safe and effective medications for older people 27: Torgeir Bruun Wyller and Erik Bautz-Holter: General principles of recovery and rehabilitation 28: Jonathan Martin, Caroline Nicholson and Rob George: The approach of dying and death, and the mourning process of the survivors 29: Reijo Tilvis: Legal and ethical issues in care of older adults Section 3: Principles and organisation of careEdited by B. Lynn Beattie: 30: Alfonso J. Cruz-Jentoft: Integrating geriatrics principles into primary care 31: Gideon Caplan: Clinical Interventions in home care 32: Don Melady and Barry J. Goldlist: Geriatric Patients in the Emergency Department 33: Maria E. Carlo, Kwame Frimpong and E. Wesley Ely: Critical Illness and Intensive Care 34: Roger Wong: Older People Presenting to Acute Care Hospitals 35: Liang-Kung Chen: Postacute Care and Intermediate Care 36: Jugdeep Dhesi and Judith Partridge: Pre-operative assessment and peri-operative management 37: Jos M. G. A. Schols and Adam Gordon: Residential and nursing home care; from the past to the future 38: Rebecca Palm and Sabine Bartholomeyczik: Dementia specialist care units 39: Elizabeth Gundersen, Benjamin A. Bensadon and Joseph G. Ouslander, M.D.: Transitions between Care Settings Till Death Section 4: Age-related biological changes, altered physiology and vulnerability to diseases and chronic conditionsEdited by Jeremy D. Walston: 40: Why do organisms agea 41: Fabbri Elisa, Zoli Marco and Ferrucci Luigi: Age-related Physiologic Declines 42: Fabbri Elisa, Zoli Marco and Ferrucci Luigi: The Emergence of Ageing Phenotypes and Multi-system decline 43: Arun S Karlamangla and Teresa E Seeman: Environment and ageing biology 44: Jintang Wang and Sean X. Leng: Inflammation and its role in ageing and disease 45: Graham Pawelec, Ludmila Müller, Tamas Fülöp: Immune system changes and immunosenescence 46: Emanuele Marzetti, Francesco Landi, Francesca Martini, Christiaan Leeuwenburgh, Riccardo Calvani: Mitochondrial Decline and Chronic Conditions of Older Adults 47: Kevin Horgan, Fergus Shanahan, Paul W. O Toole and Deborah Dunn-Walters: Biological significance of gut microbiota changes associated with ageing Section 5: Geriatric syndromes in clinical practiceEdited by Jeremy D. Walston: 48: Marcel Olde Rikkert: Conceptualizing Geriatric Syndromes 49: Alasdair MacLullich,Edward R. Marcantonio and David Meagher: Delerium 50: Clemens Becker, Jean Woo and Chris Todd: Falls 51: Adrian Wagg: Urinary Incontinence 52: Richard Savdie, Edmund CP and Mr Chidi Molokwu: Benign Prostatic Hyperplasia and Prostate Cancer 53: Cindy Kiely and Magdalena Pupiales: Pressure ulcers in the ageing population 54: José A. Morais: Sarcopenia Definitions and Epidemiology 55: Townsend Benard and Roger A. Fielding: Pathophysiology of Sarcopenia 56: Luis Miguel F. Gutiérrez Robledo and Mario Ulises Perez Zepeda: Sarcopenia: assessment, management and outcomes 57: Jeremy Walson: Frailty in older adults Section 6: Nutrition and metabolismEdited by B. Lynn Beattie: 58: Maria Isabel Toulson Davisson Correia and Simone de Vasconcelos Generoso: Epidemiology of malnutrition in different care settings 59: Francesco Landi, Anna Maria Martone, Riccardo Calvani and Emanuele Marzetti: Anorexia of Ageing 60: Jürgen M. Bauer and Rebecca Diekmann: Protein and energy requirements in health and illness 61: Heike A. Bischoff-Ferrari: Vitamin D: Its role in health and disease in older people 62: Cédric Annweiler and Olivier Beauchet: Micronutrients: their roles in health and diseases in older people 63: Gianfranco Gioia, Alessio Molfino, Filippo Rossi Fanelli, and Maurizio Muscaritoli: From nutritional screening to assessment and nutritional plan in community, acute and long term care 64: Mauro Zamboni, Francesco Fantin and Gloria Mazzali: Obesity 65: Stefania Maggi and Gaetano Crepaldi: Metabolic syndrome 66: Leocadio Rodríguez Mañas, Marta Castro Rodríguez and Alan J. Sinclair: Management of Diabetes in Older Adults. Section 7: Mobility disorders: prevention, impact and compensationEdited by Finbarr C. Martin: 67: Stephanie Studenski and Jessie Van Swearingen: Gait Disorders: Clinical Significance and Approach to Evaluation and Management 68: René Rizzoli: Osteoporosis in the oldest old: epidemiology, assessment and management 69: Hiroshi Hagino and Akiko Kondo: Common fractures in older adults: Epidemiology and outcomes 70: V. Ana Sanguineti, Jason R. Wild, Bellal Joseph and Mindy J. Fain: Management of Common Fractures in Older Adults 71: Tahir Masud and Paul J. Mitchell: Secondary prevention of fragility fractures: case finding, fracture liaison, falls reduction, injury prevention. 72: Francisco J Blanco: Osteoarthritis 73: Kieran O Sullivan, Kjartan Vibe Fersum, Wim Dankaerts and Peter O Sullivan: Low back pain in older adults: From red flags to functional rehabilitation 74: Alexis Régent and Loïc Guillevin: Vasculitides In The Elderly 75: James B Galloway and David L Scott: Management of common types of arthritis in older adults 76: Hylton B. Menz: Foot Problems 77: Tomasz Kostka and Joanna Kostka: Injuries in sports activities in elderly people 78: Jacqueline Close: Orthogeriatrics Section 8: Infections in Older Adults: Epidemiology, pathophysiology, diagnosis and managementEdited by Jean-Pierre Michel: 79: Michel Moutschen, Henri Martens and Vincent Geenen: Immunosenescence and Infectious Diseases 80: Gaëtan Gavazzi, Thibaut Fraisse, Benoit de Wazières: Epidemiology of infection in elderly populations in various settings 81: Adamantia Liapikou and Antoni Torres: Pneumonia and respiratory tract infections 82: Aparajit Ballav Dey and Ramesh Kandel: Tuberculosis in old age 83: Werner Zimmerli and Parham Sendi: Bone and Periprosthetic Joint Infections in Older Adults 84: Ursula Müller-Werdan and Karl Werdan: Infective endocarditis 85: Amy Justice: Ageing with HIV 86: Benedikt Huttner and Stephan Harbarth: Health care associated infections and emergence of antibiotic resistance 87: Pascal Astagneau, Elise Seringe and Francois Bricaire,: Healthcare-associated infections and infection control 88: Janet E. McElhaney: Vaccines against viral infections 89: Jean-Pierre Michel, Pierre-Olivier Lang and Richard Aspinall: Vaccination in older adults needs to be included a life-course programme Section 9: Cancer: Epidemiology, pathophysiology, diagnosis and managementEdited by B. Lynn Beattie: 90: Tamas Fulop, Vladimir N. Anisimov, Francis Rodier and Martine Extermann: Cell biology and carcinogenesis in the elderly 91: Shane O'Hanlon and Margot Gosney: Epidemiology of cancers in older adults 92: Anne M Horgan and Shabbir MH Alibhai: Screening for Cancer 93: Nicolò Matteo Luca Battisti and Martine Extermann: Multidisciplinary management, including chemotherapy of solid tumors (lung, breast & colon) 94: Roberto Mina, Alessandra Larocca and Antonio Palumbo: Haemopoietic diseases: Leukemias & Myelomas Section 10: Vascular diseases: Epidemiology, pathophysiology, diagnosis and managementEdited by Jeremy D. Walston: 95: Hidetaka Ota and Masahiro Akishita: Cardiac and Vascular Ageing 96: Hidenori Arai: Dyslipidemias and other cardio-metabolic risk factors In Older Adults 97: Junichiro Hashimoto, Michael F. O'Rourke: Physical factors in arterial ageing 98: Chung S Lim, Sarah Onida and Alun H Davies: Peripheral Vascular Disease in Older Adults: Diagnostic and Treatment Considerations 99: Gino Gemayel and Afksendiyos Kalangos: Aneurysmal Diseases 100: Simone Wärntges, Katrin Schäfer and Stavros V. Konstantinides: Pulmonary thromboembolism 101: Hiromi Rakugi, and Tatsuo Kawai,: Hypertension in older adults 102: R. A. Kenny and Conal Cunningham: Syncope and neurocardiovascular instability 103: Mark ONeill, John Whitaker, Jonathan Birns, and Matthew Wright: Management of Atrial Fibrillation and Anticoagulant Therapies 104: James L Harrison and Mark D O Neill: Management of Bradyarrhythmias 105: James L Harrison and Mark D O Neill: Management of Bachyarrhythmias 106: Martina Rafanelli, Francesco Orso and Niccolò Marchionni: Ischemic Heart Disease 107: Alain Cribier and Helene Eltchaninoff: Valvular Heart Disease State of the Art and Treatment Perspectives 108: John Cleland and John Baxter: Heart Failure - Definitions, Investigation & Management 109: Andrew Maiorana, Lis Neubeck, Sian Williams and Keith Hill: Cardiac Rehabilitation 110: Esther M.M. van de Glind, Barbara C. van Munster and Marije E. Hamaker: Cardiopulmonary Resuscitation: Outcomes and Decision Making Processes for Older Adults Section 11: Neurologic Disorders: Epidemiology, pathophysiology, diagnosis and managementEdited by Finbarr C. Martin: 111: Henry J. Woodford and James George: Examining the nervous system of an older patient 112: Stéphane Mathis, Pierre Bouche, Jean-Michel Vallat: Peripheral neuropathies and motor neuron disorders 113: Mark Weatherall: Headaches and Facial Pain 114: Abdullah Bin Zahid and Uzma Samadani: Traumatic brain injury and subdural hematoma 115: Steven C. Schachter: Seizure disorders and management 116: John V. Hindle, Sion Jones and Glesni Davies: Parkinsonism, Parkinson s disease and related conditions 117: Uy Hoang, Abdel Douiri, Salma Ayis, Yanzhong Wang, Anthony Rudd and Charles Wolfe: Stroke: Epidemiology, different types of strokes 118: L. Manning, M. Y. Lam, and T. G. Robinson: Primary and secondary prevention of stroke 119: Jonathan Birns and Ajay Bhalla: Management of acute stroke within the stroke pathway and stroke clinics 120: J.S. K. Kwan, M. M. Y Tse and L. S. W. Li: Neurological Rehabilitation Section 12: Cognitive decline and dementia in older adults: Epidemiology, pathophysiology, diagnosis and managementEdited by B. Lynn Beattie: 121: John Starr: Normal cognition and ageing: Structure and function, Cognitive reserve 122: Jean François Dartigues, Leslie Grasset, Maturin Tabue-Tiguo, Alexandra Foubert, Karine Pérès, Catherine Helmer and Hélène Amieva: Epidemiology of Alzheimer s Disease: a relevant challenge for long term follow-up of population-based cohort. 123: Francesca Mangialasche , Tiia Nganduand Miia Kivipelto: Cognitive impairment Risk Factors and Prevention 124: H. Tuokko and C. Smart: Neuropsychological evaluation of cognition 125: Pieter Jelle Visser, Nienke Legdeur, Mara ten Kate and Daniela Bertens: Mild Cognitive Impairment 126: Bruno Dubois, Massimo Filippi and Gunhild Waldemar: The Diagnosis of Alzheimer s Disease: Assessment and Criteria 127: Chiadi U. Onyike: Assessment and diagnosis of the non-Alzheimer dementias 128: Jacques Hugon and Claire Paquet: Pharmacological interventions in mild cognitive impairment (mci) and dementia 129: Michelle C. Carlson and Vijay R. Varma: Non-pharmacologic Behavioral Activity Interventions to Prevent Dementia 130: Gabriel Gold and Dina Zekry,: Management of co-morbidities in demented patients 131: Anne Corbett, Clive Ballard and Byron Creese: Evidence-based management of behavioural and psychological symptoms of dementia 132: Emma Reynish, Nicola Thomson and Jane Roberson: Caregivers in dementia: Role and Empowerment 133: Yohko Maki, Takashi Sakurai and Kenji Toba: A new model of care for patients with dementia: The Japanese Initiative for Dementia Care Section 13: Mental health of older adultsEdited by Jean-Pierre Michel: 134: Renzo Rozzini and Marco Trabucchi: Mental health: Epidemiology, pathophysiology, diagnosis and management 135: Yohannes Endeshaw and Donald L. Bliwise: Sleep disorders 136: Christine M. Ulbricht, Jacob Hunnicutt, Anne Hume, Camilla B. Pimentel, Jennifer Tjia and Kate L. Lapane: Mood and Anxiety Disorders 137: Luis Agüera-Ortiz: Functional psychoses 138: Ilana Crome and Rahul (Tony) Rao: Older people with substance problems 139: Peter Crome and Amit Arora: Elder Abuse Section 14: Management of Common medical conditions: epidemiology, pathophysiology, diagnosis and managementEdited by Finbarr C. Martin: 140: Simon Conroy and Rosa McNamara: Common geriatric emergencies 141: Natalie Ebert and Elke Schaeffner: Management of acute kidney injury and chronic kidney disease 142: Michael I Macentee: Oral Health and Mouth Diseases. 143: Silvia Carrión and Pere Clavé: Gastrointestinal disease in the older population 144: Philippe Ducrotte and Philippe Chassagne: Malabsorption 145: Philippe Chassagne and Frédéric Roca: Constipation and faecal incontinence 146: Chang Won Won and Sunyoung Kim: Age-associated breathlessness 147: Ammon M. Fager and Harvey Jay Cohen: Anaemia 148: Alexis McKee and John E. Morley: Endocrinology of Ageing 149: Marcello Maggio, Fulvio Lauretani and Gian Paolo Ceda: Sexuality in Older Persons 150: Christophe Trivalle and Daniel Wallach: Skin diseases more common in older adults 151: Jacqueline Chua, Ching-Yu Cheng and Tien Yin Wong: Common age-related eye diseases and visual impairment 152: Sara K. Mamo, Theresa H. Chisolm and Frank R. Lin: Hearing impairments and their treatments 153: Declan Lyons, Avril Bierne and Joanna Lawson: Dizziness and Vertigo Section 15: Palliative medicine and end of life careEdited by Jean-Pierre Michel: 154: Why, when, and where do older people diea 155: Viviana Forte and Giovanni Gambassi: Prognostication and Recognition of dying 156: Nele Van Den Noortgate and Elizabeth Sampson: Pain assessment and management in cognitively intact and impaired patients 157: Nele Van Den Noortgate and Elizabeth Sampson: Symptom assessment and management at the end of life 158: Finbarr C Martin, Abdul Abyad, Hidenori Arai, Marcel Arcand, Hashim Hasan Balubaid, B Lynn Beattie, Yitshal N. Berner, Rajiv Mohan Kaushik, Pedro Paulo Marín, Yasuyoshi Ouchi, Marwan Ramadan and Paulina Taboada: Eating and Drinking in Later Life 159: Rehabilitation: additional palliative care approaches 160: Aline De Vleminck and Luc Deliens: Advance Care Planning for Older People Section 16: Healthy ageingEdited by Jeremy D. Walston: 161: Sebastiano Collino, Blandine Comte, Estelle Pujos Guillot, Claudio Franceschi, Antonio Nuñez Galindo, Loïc Dayon and Martin Kussmann: Healthy Ageing Phenotypes and Trajectories 162: Ina Voelcker and Alexandre Kalache: Empowerment of the ageing population: a contribution to active ageing 163: Timo E. Strandberg: Midlife risk factors of diseases and geriatric syndromes 164: Stephen D. Anton, Duane Corbett and Todd Manini: Optimizing Physical Activity Across the Lifespan 165: Tommy Cederholm and Mai-Lis Hellénius: Nutrition, ageing and longevity 166: Nicoletta Berardi, Alessandro Sale and Lamberto Maffei: Optimizing cognition in older adults: lifestyle factors, neuroplasticity, cognitive reserve. 167: Osvaldo P. Almeida: Preserving Mental Health and Well-Being 168: Allyson K. Palmer and James L. Kirkland: Clinical Translation of Interventions that Target Ageing: Toward a Longevity Dividend 169: Benjamin Shapiro and L. Jaime Fitten,: Driving, transportation and mobility in the older adult 170: James Podrebarac, Joel Edin, Erik J. Suuronen, Emilio I. Alarcon and May Griffith: Nanosciences and the Medicine of Ageing 171: Tilak Dutta, Babak Taati, Pam Holliday, Yue Li, Steve Pong, Alex Mihailidis and Geoffrey Fernie: Gerontechnology 172: Gunnar Akner: Personalized Medicine for Older Adults 173: Jean-Pierre Michel, B. Lynn Beattie, Finbarr C. Martin and Jeremy Walston: What next for Geriatric Medicine? Index

Provides up-to-date research highlighting the current state of progress in life course research studies The global span of the book provides multi-cultural approaches to care organization, specifically within the last period of life Highlights practical aspects for the promotion of 'healthy ageing', well-functioning, and wellness in an ever more demanding world

Dr Michel is Emeritus Professor of Medicine, former head of the academic Geriatric Department, Geneva University, and honorary professor in France, China and Quebec. He co-founded the European, Middle-East, Latin-America and Asian Academy for Medicine of Ageing and the European Interdisciplinary Council on Ageing. He is past President of the European Union Geriatric Medicine Society and editor-in-chief of European Geriatric Medicine. Dr Michel is also a full board member of the French Academy of Medicine and has received an IAGG World Award for his life-time and global achievements in Geriatrics. He is an ongoing World Health Organization expert for the 'Aging and Life course' program, and contributed to the 1st WHO report on Healthy Ageing in 2015. He has also authored 430 peer reviewed papers and numerous book chapters. B Lynn Beattie is Professor Emeritus, Division of Geriatric Medicine, Department of Medicine, UBC. Her current clinical interest is practise at the UBC Hospital Clinic for Alzheimer Disease and Related Disorders (UBCH CARD) where she is the Medical Director. She is on the Board of the Alzheimer Society of Canada as Chair of the Research Policy Committee and has completed two terms as Secretary Treasurer of C5R, the Consortium of Canadian Centres for Clinical Cognitive Research. Professor Beattie also started and was the first Head of the Division of Geriatric Medicine at UBC, initially based at Shaughnessy Hospital and in later years at Vancouver Coastal UBC/VGH. She was Director of the Clinic for Alzheimer's Disease and Related Disorders from its inception until 2005, and again from 2009 to date, and is Past President of the American Geriatrics Society and the Canadian Geriatrics Society. Professor Finbarr C. Martin trained in geriatric medicine at Hammersmith Hospital, London, and was appointed consultant physician in general and geriatric medicine at St Thomas' Hospital in 1984. He has worked in a broad range of services for older people in acute hospitals and in community settings. He has led national audit programmes on falls and fragility fractures, and is co-chair of the DH funded but clinically led National Hip Fracture Database. He was the elected president of the British Geriatrics Society between 2010 and 2012. Dr Jeremy Walston is a professor of medicine at the Johns Hopkins University School of Medicine. His area of clinical expertise is geriatric medicine. At the Johns Hopkins School of Medicine, Dr Walston is co-director of the Biology of Healthy Aging Program in the Division of Geriatric Medicine and Gerontology as well as deputy director of the division, and the Raymond and Anna Lublin Professor of Geriatric Medicine. Dr Walston plays a leading role in setting the national ageing research agenda through his leadership and participation in committees of the American Geriatrics Society and on study sections and review panels for the National Institute on Aging. He has won numerous awards for his research, including the American Geriatrics Society New Investigator Award, a Brookdale National Leadership Fellowship and Paul Beeson Physician Faculty Scholars recognition.

Provides up-to-date research highlighting the current state of progress in life course research studies The global span of the book provides multi-cultural approaches to care organization, specifically within the last period of life Highlights practical aspects for the promotion of 'healthy ageing', well-functioning, and wellness in an ever more demanding world