This book presents a systematic review of research concerning processes and systems in Emergency Departments (EDs), the issues faced by EDs, and their solutions to ensure the delivery of proper and ideal healthcare services for patients through superior quality process management. The book evaluates two decades of data, from 2000 to 2019, in order to examine the processes used in ED operations. Emergency Department has become evident particularly in the current scenario when the world is in the grip of the deadly COVID-19. The two decades of data revealed a lack of literary content on bringing improvement for EDs in Malaysia and Saudi Arabia through the deployment of simulation models. Simulation model in Malaysia and Saudi Arabia is being considered for the first time by this book.