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This revised and updated new edition of a successful book is a multidisciplinary, comprehensive guide to occupational factors of malignant diseases.

Building on the first edition, new research discoveries and their consequences in our understanding on carcinogenic mechanisms, diagnosis and attribution of occupational cancers are discussed. Examples of such discoveries are germline and acquired mutations of BAP1 in malignant mesothelioma, which have led to changes in diagnostic criteria, and carcinogen-specific genetic and epigenetic alterations in lung cancer. There are several new chapters, including gastrointestinal cancers, epidemiology of lung cancer, cancer of thyroid, and the role of primary health care in occupational cancer control.

Occupational Cancers is aimed at experienced and trainee oncologists, pathologists, clinicians in occupational health, and pulmonologists, as well as epidemiologists, clinical researchers, lawyers and public health officials.

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Historical Overview of Occupational Cancer Research.- Genetics, Epigenetics and Environmental Interactions.- Mechanisms of Environmental and Occupational Carcinogenesis.- Head and Neck Cancers.- Cancers of the Gastrointestinal Tract (Esophageal, Gastric and Colorectal Cancer).- Pancreatic Cancer.- Sinonasal Cancer.- Cancers of the Intestine, the Liver and the Biliary Tract.- Occupational Risk Factors of Laryngeal Cancer.- Lung Cancer: Clinical Findings, Pathology and Exposure Assessment.- Lung Cancer: Molecular Markers.- Lung Cancer: Mechanisms of Carcinogenesis by Asbestos.- Lung cancer: Mechanisms and Markers – Carcinogens other than Asbestos.- Lung Cancer: Genetic Susceptibility.- Epidemiology of Occupational Lung Cancer.- Malignant Mesothelioma: Clinical and Imaging Findings.- Malignant Mesothelioma: Pathology.- Malignant Mesothelioma: Molecular Markers.- Malignant Mesothelioma: Mechanism of Carcinogenesis.- Malignant Mesothelioma: Asbestos Exposure.- Epidemiology of Mesothelioma.-Soft Tissue and Bone Sarcomas.- Malignant Neoplasms of the Skin.- Breast Cancer.- Malignant Tumours of the Female Reproductive System.- Malignant Tumours of the Male Reproductive System.- Kidney cancer.- Bladder cancer.- Malignant Tumors of the Central Nervous System.- Occupational Exposures and Thyroid Cancer.- Lymphohematopoietic Malignancies.- Occupational Cancer Burden.- Occupational Carcinogens and Cancer in Children.- Strategies for Primary Prevention of Occupational Cancer.- Screening for Occupational Cancer.- Occupational Cancer in the Practice of Occupational Medicine.- The Use of Register Data in Occupational Cancer Control.- Appendix.

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This revised and updated new edition of a successful book is a multidisciplinary, comprehensive guide to occupational factors of malignant diseases.

Building on the first edition, new research discoveries and their consequences in our understanding on carcinogenic mechanisms, diagnosis and attribution of occupational cancers are discussed. Examples of such discoveries are germline and acquired mutations of BAP1 in malignant mesothelioma, which have led to changes in diagnostic criteria, and carcinogen-specific genetic and epigenetic alterations in lung cancer. There are several new chapters, including gastrointestinal cancers, epidemiology of lung cancer, cancer of thyroid, and the role of primary health care in occupational cancer control.

Occupational Cancers is aimed at experienced and trainee oncologists, pathologists, clinicians in occupational health, and pulmonologists, as well as epidemiologists, clinical researchers, lawyers and public health officials.

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Includes new organ- and topic-oriented chapters Covers epidemiology, clinical features and pathology, as well as molecular carcinogenic mechanisms and biomarkers Emphasizes prevention at an individual level as well as in populations and familiarizes readers with preventive strategies
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GPSR Compliance The European Union's (EU) General Product Safety Regulation (GPSR) is a set of rules that requires consumer products to be safe and our obligations to ensure this. If you have any concerns about our products you can contact us on ProductSafety@springernature.com. In case Publisher is established outside the EU, the EU authorized representative is: Springer Nature Customer Service Center GmbH Europaplatz 3 69115 Heidelberg, Germany ProductSafety@springernature.com
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Produktdetaljer

ISBN
9783030307684
Publisert
2021-08-26
Utgave
2. utgave
Utgiver
Vendor
Springer Nature Switzerland AG
Høyde
279 mm
Bredde
210 mm
Aldersnivå
Professional/practitioner, P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet
Orginaltittel
Occupational Cancers

Biographical note

Paolo Boffetta, MD, MPH gained his medical degree from the University of Turin in 1984. He gained his MPH from the University of Columbia, New York in 1998, at the same time as his Specialization in Public Health from the University of Turin, Italy. He then held roles in the area of cancer epidemiology and public health in the US, France, Germany, Italy, Canada, Greece, the UK and Sweden. He is currently Associate Director for Global Oncology at the Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA, and Professor of Occupational Medicine at the Department of Medical and Surgical Sciences, University of Bologna, Italy.

Sisko Anttila, MD, PhD, is Head of Pulmonary Pathology at the Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. Previously, she worked as chief physician and pathologist at the Finnish Institute of Occupational Health, Helsinki, Finland. Her research has concentrated on gene-environment interactions in pulmonary carcinogenesis, including tobacco-derived carcinogens and asbestos. Dr. Anttila has special interest in pulmonary pathology, especially pathology of occupational lung diseases and malignant mesothelioma. She was a member of a working group establishing international criteria for asbestos-related diseases (Asbestos, Asbestosis, and Cancer, Helsinki Criteria for Diagnosis and Attribution 2014).