On December 5, 2017, the National Academies of Sciences, Engineering, and Medicine hosted a public workshop titled Nutrigenomics and the Future of Nutrition in Washington, DC, to review current knowledge in the field of nutrigenomics as it relates to nutrition. Workshop participants explored the influence of genetic and epigenetic expression on nutritional status and the potential impact of personalized nutrition on health maintenance and chronic disease prevention. This publication summarizes the presentations and discussions from the workshop.Table of ContentsFront Matter1 Introduction2 Nutrigenomics and Chronic Disease Endpoints3 Personalized Nutrition in the Real World4 Nutrigenomics Applications: Dietary Guidance and Food Product Development5 Nutrigenomics: Regulatory, Ethical, and Science Policy Considerations6 Rethinking the Relationship Between Diet and Health: Can Nutrigenomics Help?ReferencesAppendix A: Workshop AgendaAppendix B: Acronyms and AbbreviationsAppendix C: Speaker and Facilitator Biographies