In this issue of PET Clinics, guest editors Drs. Cristina Nanni, Paolo Castellucci, Stefano Fanti, and Neeta Pandit-Taskar bring their considerable expertise to the topic of Novel PET Imaging Techniques in the Management of Hematological Malignancies. Top experts in the field discuss the latest radiotracers for lymphoma and myeloma, novel quantitative imaging techniques, radioligand therapies, total body PET imaging; and more. Contains 15 relevant, practice-oriented topics including PET imaging for therapy assessment in Hodgkin and non-Hodgkin lymphomas; symptomatic myeloma: PET, WB-MRI with DWI or both; advantages of total body PET imaging in hematological malignancies; applications of FDG-PET imaging in leukemias; PET imaging for therapy assessment in symptomatic myeloma, including Minimal Residual Disease; and more. Provides in-depth clinical reviews on novel PET imaging techniques in the management of hematological malignancies, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.