An update on current knowledge is given for surgeons and researchers involved in implant surgery and the development of implant arthroplasty. These include: detailed data on the microscopy of the junctional tissues, the mechanical properties of cement, and the architecture of bone and implant design.

I Histology of the Junctional Tissues.- 1 An Overview of the Histology of the Principal Interface Types in Orthopaedic Surgery Today.- 2 Biological Factors of Importance for Bone Integration of Implanted Devices.- 3 The Reaction of Bone to Bone Cement in Animals and Humans.- 4 New Observations on the Bone Cement—Bone Interface.- 5 Morphology of Implant—Bone Interface in Cemented and Non-cemented Endoprostheses.- 6 Tissue Reactions to Metallic Biomaterials.- 7 Osseo-integration of Metallic Implants in Animals and Humans.- 8 Histology of the Failed Implant.- 9 The Effects of Wear Particles on Periprosthetic Tissues.- 10 Failure Modes of Artificial Joint Implants Due to Particulate Implant Material.- 11 Pathology of Cemented Low-Friction Arthroplasties in Autopsy Specimens.- II Bone Cement.- 12 Time-Dependent Properties of Polymethylmethacrylate Bone Cement.- 13 The Scientific Basis of Vacuum Application of Bone Cement.- 14 Intrafemoral Pressure in Total Hip Replacement.- III Bone.- 15 Bone: The Architecture of Bone and How it is Influenced by External Loading.- IV Miscellaneous.- 16 Endosteal Lysis.- 17 Micro-motion: Consequences of Material Choices, Implant Design and Fit.- 18 Differential Movement Between Implant and Bone.- 19 A Preliminary Report on the Stem-Cement Interface and its Influence on the Bone-Cement Interface.- 20 Calcar/Collar Contact in Cemented Total Hip Arthroplasty.- 21 Trial of Cementless Versus Cemented Total Hip Arthroplasty: Preliminary Results.- 22 Intramedullary Cement Fixation: A Comparison of the Fixation of Custom-Made Prostheses with the Fixation of Standard Joint Replacements.- 23 Hydroxyapatite Crystals in Bone Ingrowth and Comparison of Autografts and Allographs: Preliminary Report.- 24 Fluoroscopically Controlled Radiographs inExamination of the Bone-Implant Interface: Preliminary Results.- 25 Conclusion.

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