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Application of Nanocarriers in Brain Delivery of Therapeutics

Alexander, Amit
Innbundet / 2024 / Engelsk

Produktdetaljer

ISBN
9789819728589
Publisert
2024-09-07
Utgiver
Vendor
Springer Nature
Høyde
235 mm
Bredde
155 mm
Aldersnivå
Research, P, 06
Språk
Product language
Engelsk
Format
Product format
Innbundet

Redaktør
Alexander, Amit

Biographical note

Dr. Amit Alexander is an Associate Professor in the Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, under the aegis of the Department of Pharmaceuticals (DoP), Ministry of Chemicals and Fertilizers, Government of India (GoI). He has overall academic experience of more than 13 years in Novel drug delivery systems, Pharmacokinetics, Biopharmaceutics, Statistical Design, Drug Targeting approaches, etc. He is an active member of the Royal Society of Chemistry (MRSC), London, United Kingdom (UK), Royal Society of Biology (MRSB), London, United Kingdom (UK), Controlled Release Society-Indian Local Chapter (CRS-IC), Mumbai, Indian Academy of Neuroscience (IAN) and a life fellow of Indian Chemical Society (FICS), Kolkata. His research interest is in pharmaceutical dosage form development, novel drug delivery systems focusing on nanoparticles and stimuli-responsive hydrogels for critical pathophysiological conditions mainly for brain disorders and tumor targeting. Dr. Alexander specifically works on controlled release and targeting of the drug by utilizing novel approaches. He has been conferred with various prestigious awards notably, UGC-JRF 2011, Dr. P. D. Sethi Annual Award-2012, Young Scientist at Chhattisgarh Young Scientists Congress-2013, Young Researcher Award-2020, First Prize in several National and International conferences, and many Foreign Travel Grants from Government agencies like SERB, DST, CSIR, ICMR for presenting his research work. He has been listed in the Top 2% scientists from India in World Ranking for 2 consecutive years (2020 & 2021) by Stanford University, USA. He has served as a referee for a number of SCI-indexed International journals and is also serving as a review editor in Frontier in Biomaterial Journal. He has presented many invited talks and oral presentations at various International and National scientific peer conferences and attended seminars and conferences as keynote speaker/chairperson and evaluator.

Application of Nanocarriers in Brain Delivery of Therapeutics

Alexander, Amit
Innbundet / 2024 / Engelsk
Alexander, Amit
Innbundet / 2024 / Engelsk
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This book presents nanoparticles as potential drug delivery carriers for overcoming the blood-brain barrier. The initial chapter of the book discusses complex brain disorders, the currently available therapies, and their limitations. The book discusses the potential applications of polymeric nanoparticles, lipid nanocarriers, liposomes, inorganic nanoparticles, dendrimers, and stimuli-responsive polymers for targeted brain drug delivery. Further, it evaluates the development and role of different cell lines and animal models in brain research. Towards the end, the book reviews challenges, safety, toxicity, regulatory aspects, future possibilities, and constraints in the clinical translation of nanocarrier systems to treat neurological disorders. The book as such provides valuable information to neuroscientists, and researchers working in pharmaceuticals, nanomedicine, drug delivery research, and nanotechnology. ​
Les mer
This book presents nanoparticles as potential drug delivery carriers for overcoming the blood-brain barrier. The book discusses the potential applications of polymeric nanoparticles, lipid nanocarriers, liposomes, inorganic nanoparticles, dendrimers, and stimuli-responsive polymers for targeted brain drug delivery.
Les mer
Chapter 1. Introduction to complex brain disorders, currently available therapies, and their limitations.- Chapter 2. Challenges of brain targeting and mechanism of drug transfer across BBB.- Chapter 3. Introduction to nanoparticles as a potential carrier for brain targeting.- Chapter 4. Application of polymeric nanoparticles in brain targeting.- Chapter 5. Recent advancements in lipid nanocarriers for brain delivery of bioactive.- Chapter 6. Liposomes as a potential carrier for brain delivery.- Chapter 7. Inorganic nanoparticles for brain targeting: scope and limitations.- Chapter 8. Potential of dendrimers as a nanocarrier for brain delivery.- Chapter 9. Surface active ligands for enhanced brain targeting of nanoparticles.- Chapter 10. Stimuli-responsive polymers for brain delivery.- Chapter 11. In vitro cell line development and their limitations for brain research.- Chapter 12. In vivo Animal model development and their limitation for brain research.- Chapter 13. Safety, stability concerns, and regulatory aspects of Nanocarriers for brain delivery.- Chapter 14. Current clinical advancements of nanocarriers for brain targeting and limitations in clinical translation.
Les mer
This book presents nanoparticles as potential drug delivery carriers for overcoming the blood-brain barrier. The initial chapter of the book discusses complex brain disorders, the currently available therapies, and their limitations. The book discusses the potential applications of polymeric nanoparticles, lipid nanocarriers, liposomes, inorganic nanoparticles, dendrimers, and stimuli-responsive polymers for targeted brain drug delivery. Further, it evaluates the development and role of different cell lines and animal models in brain research. Towards the end, the book reviews challenges, safety, toxicity, regulatory aspects, future possibilities, and constraints in the clinical translation of nanocarrier systems to treat neurological disorders. The book as such provides valuable information to neuroscientists, and researchers working in pharmaceuticals, nanomedicine, drug delivery research, and nanotechnology.
Les mer
Presents nanocarriers as potential drug delivery candidates for overcoming the blood-brain barrier Introduces different cell lines and animal models involved in brain research Discusses nanoparticulate system for brain delivery of drugs and reviews their safety assessment
Les mer
GPSR Compliance The European Union's (EU) General Product Safety Regulation (GPSR) is a set of rules that requires consumer products to be safe and our obligations to ensure this. If you have any concerns about our products you can contact us on ProductSafety@springernature.com. In case Publisher is established outside the EU, the EU authorized representative is: Springer Nature Customer Service Center GmbH Europaplatz 3 69115 Heidelberg, Germany ProductSafety@springernature.com
Les mer

Relaterte produkter

This book presents nanoparticles as potential drug delivery carriers for overcoming the blood-brain barrier. The initial chapter of the book discusses complex brain disorders, the currently available therapies, and their limitations. The book discusses the potential applications of polymeric nanoparticles, lipid nanocarriers, liposomes, inorganic nanoparticles, dendrimers, and stimuli-responsive polymers for targeted brain drug delivery. Further, it evaluates the development and role of different cell lines and animal models in brain research. Towards the end, the book reviews challenges, safety, toxicity, regulatory aspects, future possibilities, and constraints in the clinical translation of nanocarrier systems to treat neurological disorders. The book as such provides valuable information to neuroscientists, and researchers working in pharmaceuticals, nanomedicine, drug delivery research, and nanotechnology. ​
Les mer
This book presents nanoparticles as potential drug delivery carriers for overcoming the blood-brain barrier. The book discusses the potential applications of polymeric nanoparticles, lipid nanocarriers, liposomes, inorganic nanoparticles, dendrimers, and stimuli-responsive polymers for targeted brain drug delivery.
Les mer
Chapter 1. Introduction to complex brain disorders, currently available therapies, and their limitations.- Chapter 2. Challenges of brain targeting and mechanism of drug transfer across BBB.- Chapter 3. Introduction to nanoparticles as a potential carrier for brain targeting.- Chapter 4. Application of polymeric nanoparticles in brain targeting.- Chapter 5. Recent advancements in lipid nanocarriers for brain delivery of bioactive.- Chapter 6. Liposomes as a potential carrier for brain delivery.- Chapter 7. Inorganic nanoparticles for brain targeting: scope and limitations.- Chapter 8. Potential of dendrimers as a nanocarrier for brain delivery.- Chapter 9. Surface active ligands for enhanced brain targeting of nanoparticles.- Chapter 10. Stimuli-responsive polymers for brain delivery.- Chapter 11. In vitro cell line development and their limitations for brain research.- Chapter 12. In vivo Animal model development and their limitation for brain research.- Chapter 13. Safety, stability concerns, and regulatory aspects of Nanocarriers for brain delivery.- Chapter 14. Current clinical advancements of nanocarriers for brain targeting and limitations in clinical translation.
Les mer
This book presents nanoparticles as potential drug delivery carriers for overcoming the blood-brain barrier. The initial chapter of the book discusses complex brain disorders, the currently available therapies, and their limitations. The book discusses the potential applications of polymeric nanoparticles, lipid nanocarriers, liposomes, inorganic nanoparticles, dendrimers, and stimuli-responsive polymers for targeted brain drug delivery. Further, it evaluates the development and role of different cell lines and animal models in brain research. Towards the end, the book reviews challenges, safety, toxicity, regulatory aspects, future possibilities, and constraints in the clinical translation of nanocarrier systems to treat neurological disorders. The book as such provides valuable information to neuroscientists, and researchers working in pharmaceuticals, nanomedicine, drug delivery research, and nanotechnology.
Les mer
Presents nanocarriers as potential drug delivery candidates for overcoming the blood-brain barrier Introduces different cell lines and animal models involved in brain research Discusses nanoparticulate system for brain delivery of drugs and reviews their safety assessment
Les mer
GPSR Compliance The European Union's (EU) General Product Safety Regulation (GPSR) is a set of rules that requires consumer products to be safe and our obligations to ensure this. If you have any concerns about our products you can contact us on ProductSafety@springernature.com. In case Publisher is established outside the EU, the EU authorized representative is: Springer Nature Customer Service Center GmbH Europaplatz 3 69115 Heidelberg, Germany ProductSafety@springernature.com
Les mer

Produktdetaljer

ISBN
9789819728589
Publisert
2024-09-07
Utgiver
Vendor
Springer Nature
Høyde
235 mm
Bredde
155 mm
Aldersnivå
Research, P, 06
Språk
Product language
Engelsk
Format
Product format
Innbundet

Redaktør
Alexander, Amit

Biographical note

Dr. Amit Alexander is an Associate Professor in the Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, under the aegis of the Department of Pharmaceuticals (DoP), Ministry of Chemicals and Fertilizers, Government of India (GoI). He has overall academic experience of more than 13 years in Novel drug delivery systems, Pharmacokinetics, Biopharmaceutics, Statistical Design, Drug Targeting approaches, etc. He is an active member of the Royal Society of Chemistry (MRSC), London, United Kingdom (UK), Royal Society of Biology (MRSB), London, United Kingdom (UK), Controlled Release Society-Indian Local Chapter (CRS-IC), Mumbai, Indian Academy of Neuroscience (IAN) and a life fellow of Indian Chemical Society (FICS), Kolkata. His research interest is in pharmaceutical dosage form development, novel drug delivery systems focusing on nanoparticles and stimuli-responsive hydrogels for critical pathophysiological conditions mainly for brain disorders and tumor targeting. Dr. Alexander specifically works on controlled release and targeting of the drug by utilizing novel approaches. He has been conferred with various prestigious awards notably, UGC-JRF 2011, Dr. P. D. Sethi Annual Award-2012, Young Scientist at Chhattisgarh Young Scientists Congress-2013, Young Researcher Award-2020, First Prize in several National and International conferences, and many Foreign Travel Grants from Government agencies like SERB, DST, CSIR, ICMR for presenting his research work. He has been listed in the Top 2% scientists from India in World Ranking for 2 consecutive years (2020 & 2021) by Stanford University, USA. He has served as a referee for a number of SCI-indexed International journals and is also serving as a review editor in Frontier in Biomaterial Journal. He has presented many invited talks and oral presentations at various International and National scientific peer conferences and attended seminars and conferences as keynote speaker/chairperson and evaluator.

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