Scientific advances during the last decade now indicate that Alzheimer's disease is a continuous, progressive cognitive disease, most likely beginning many years before dementia is apparent. To discuss the next steps in validating new diagnostic guidelines for Alzheimer's disease, the IOM Forum on Neuroscience and Nervous System Disorders hosted a public workshop session at the Alzheimer's Association International Conference.Table of ContentsFront MatterAlzheimer's Diagnostic Guideline Validation: Exploration of Next Steps: Workshop SummaryAppendix A: ReferencesAppendix B: Workshop AgendaAppendix C: Speaker Biographies