This book presents selected essays on the epistemological foundation of the Islamic world-system, in the light of the exegesis of the Qur’an, to develop existing understandings of Islamic economics. A selection of key contributions by one of the world's leading figures working at the nexus of Islamic social sciences, Islamic philosophy, and Islamic economics, the book integrates applied foundations of Islamic economics and Islamic philosophy, presenting a critical outlook on the existing state of Islamic economics and Islamic finance, within a broader framework of socio-scientific enquiry, philosophical perspectives on Islam, and philosophy of science. The author confronts the absence of epistemic groundwork upon which any fresh social and scientific enquiry is developing in Islamic economics, casting the discussion within an explanatory framework of ‘the unity of knowledge’ as bestowed by Islamic monotheistic law, which substantively characterizes the generalization and details of ‘everything’. The present work unravels this objective methodology and its application with reference to a limited number of issues and problems in global economics. Complex and multidisciplinary in its treatment, this book presents the key arguments on mathematical, philosophical, and socio-scientific modes of inquiry in deriving, developing, and empirically applying the Qur’anic methodology of the “unity of knowledge” to economic problems. It is relevant to scholars and advanced students in social scientific studies of Islam, Islamic theology and philosophy, and Islamic economics and finance.